Cattle Drive Casserole

A hearty, layered casserole that combines seasoned ground beef, a tender biscuit base, a creamy sour cream layer, salsa pockets and melted cheddar — perfect for weeknights or potlucks.

introduction

Cattle Drive Casserole is a comforting, crowd-pleasing dish that layers a quick biscuit crust with seasoned beef, a creamy tangy middle, and plenty of cheese. It’s straightforward to assemble, and bakes into a warm, satisfying one-dish meal that serves a family or a gathering with minimal fuss.

why make this recipe

  • Fast to assemble using pantry staples and a biscuit mix for the base.
  • Layers of flavor and texture: crisped biscuit crust, savory beef, creamy filling, and melted cheese.
  • Great for feeding a crowd, bringing to potlucks, or meal prepping for easy leftovers.
  • Flexible — easy to adapt to heat level, cheeses, or add-ins.

how to make Cattle Drive Casserole

In short: brown and season the beef, prepare and pre-bake a pressed biscuit crust, layer the beef on top, spread a creamy sour-cream/mayo/chile mixture, dot with salsa, top with shredded cheese, then bake until bubbling. The process is mostly stovetop for the filling and a single return to the oven to finish the assembled dish.

Ingredients :

Equipment

  • Large skillet
  • 2 Medium mixing bowls
  • 9 x 13” casserole dish

Ingredients

  • 1.5 pounds Lean Ground Beef
  • 1 Red Bell Pepper, seeded, chopped
  • 1 Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix
  • 2 ½ cups Biscuit Mix, like Bisquick
  • 1 cup Water
  • Cooking Spray, like Pam
  • ½ cup Sour Cream
  • ½ cup Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1 ½ cups Cheddar Cheese, Fiesta Blend, shredded, divided
  • 1 teaspoon Garlic Powder
  • ½ cup Salsa, mild

Directions :

  1. Preheat the Oven: Set the oven to 350℉.
  2. Cook the Ground Beef: Heat a skillet over medium-high heat. Add the ground beef and break it apart with a spoon. Cook until no longer pink, stirring occasionally. Drain off any excess fat. (While the meat cooks, you can prepare the biscuit dough.)
  3. Prepare the Biscuit Dough: In a mixing bowl, combine the biscuit mix and water. Stir until well mixed, ideally using your hands for thorough blending. Spray a casserole dish with cooking spray and press the dough into the dish, spreading it out to the edges. Bake in the preheated oven for 5-8 minutes, or until the dough is set and lightly golden. Set aside, but keep the oven on.
  4. Cook the Vegetables: Add chopped onions and red bell pepper to the cooked ground beef. Stir and cook for about 4 minutes. Add taco seasoning and mix well. Remove from heat.
  5. Assemble the Layers: Spread the cooked ground beef mixture evenly on top of the baked biscuit layer.
  6. Prepare the Sour Cream Layer: In a medium bowl, combine sour cream, mayonnaise, drained green chiles, ¾ cup shredded cheese, and garlic powder. Mix until smooth. Carefully spread this mixture over the ground beef layer.
  7. Add Salsa and Cheese: Add small spoonfuls of salsa over the sour cream layer (no need to spread it out). Sprinkle the remaining shredded cheese evenly on top.
  8. Bake: Place the casserole back in the oven, uncovered, and bake for 30 minutes or until hot and bubbly.

Cattle Drive Casserole

how to serve Cattle Drive Casserole

  • Let the casserole rest 5–10 minutes after baking so it sets for cleaner slices.
  • Serve with fresh garnishes: chopped cilantro, sliced green onions, or a dollop of extra sour cream.
  • Offer sides like a simple green salad, tortilla chips, or Spanish rice to round out the meal.

how to store Cattle Drive Casserole

  • Refrigerator: Cool completely, cover tightly with foil or plastic wrap, and refrigerate for up to 3–4 days.
  • Reheat: Warm individual portions in the microwave (1–2 minutes) or reheat in a 350℉ oven until heated through (about 15–20 minutes). Cover with foil if the cheese is browning too much.
  • Freezing: For best texture, freeze baked portions in airtight containers for up to 2 months. Thaw overnight in the refrigerator before reheating.

tips to make Cattle Drive Casserole

  • Don’t overwork the biscuit dough; press it evenly but avoid compacting it too much to keep a tender crust.
  • Drain excess fat from the beef to prevent a soggy middle layer.
  • If you prefer more heat, use medium or hot salsa and/or add a pinch of cayenne.
  • For extra flavor, brown the beef with a little minced garlic or a splash of Worcestershire sauce.
  • If the top browns too quickly while baking, loosely tent with foil.

variation (if any)

  • Vegetarian: Substitute cooked lentils, crumbled firm tofu, or seasoned textured vegetable protein for the ground beef.
  • Different crust: Use refrigerated biscuit dough rounds pressed together, cornbread mix, or a masa/masa harina crust for a Southwestern twist.
  • Cheese and spice: Swap cheeses (Monterey Jack, Pepper Jack, or a Mexican blend) and add jalapeños or chopped pickled peppers for more heat.

Cattle Drive Casserole

FAQ

Q: Can I make the biscuit base ahead of time?
A: Yes — you can pre-bake the biscuit layer and refrigerate it until assembly; warm slightly before adding the beef layer.

Q: Can I use homemade biscuit dough instead of mix?
A: Absolutely. A basic homemade biscuit dough will work; adjust baking time as needed until set and lightly golden.

Q: Is this freezer-friendly?
A: Baked portions freeze best. Assemble and bake, then cool and freeze portions for up to 2 months. Thaw overnight before reheating.

Conclusion

For the original source and a quick reference to the classic preparation, see Cattle Drive Casserole – The Country Cook.

Cattle Drive Casserole

A hearty, layered casserole that combines seasoned ground beef, a tender biscuit base, a creamy sour cream layer, salsa pockets, and melted cheddar — perfect for weeknights or potlucks.
Prep Time 20 minutes
Cook Time 40 minutes
Total Time 1 hour
Servings: 8 servings
Course: Dinner, Main Course
Cuisine: American, Comfort Food
Calories: 350

Ingredients
  

For the Biscuit Base
  • 2.5 cups Biscuit Mix, like Bisquick
  • 1 cup Water
  • Cooking Spray, like Pam For greasing the casserole dish
For the Meat Filling
  • 1.5 pounds Lean Ground Beef Cooked until no longer pink
  • 1 medium Red Bell Pepper, seeded, chopped
  • 1 medium Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix
  • 1 teaspoon Garlic Powder
For the Creamy Layer
  • ½ cup Sour Cream
  • ½ cup Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1.5 cups Cheddar Cheese, Fiesta Blend, shredded, divided Reserve ¾ cup for the creamy layer and the rest for topping
For Assembling
  • ½ cup Salsa, mild To dot over the sour cream layer

Method
 

Preparation
  1. Preheat the oven to 350℉.
  2. In a skillet over medium-high heat, add the ground beef and cook until browned, stirring occasionally. Drain off excess fat.
  3. In a mixing bowl, combine biscuit mix and water until well mixed. Press the dough into a greased casserole dish and bake for 5-8 minutes until set and lightly golden.
  4. Add chopped onions and red bell pepper to the cooked ground beef. Cook for about 4 minutes, then add taco seasoning and mix well. Remove from heat.
Assembling
  1. Spread the ground beef mixture evenly over the baked biscuit layer.
  2. In a bowl, combine sour cream, mayonnaise, green chiles, ¾ cup shredded cheese, and garlic powder. Mix until smooth and spread over the beef layer.
  3. Dot small spoonfuls of salsa over the sour cream layer and sprinkle the remaining cheese on top.
Baking
  1. Bake the assembled casserole in the oven uncovered for 30 minutes or until hot and bubbly.

Notes

Let the casserole rest 5–10 minutes after baking for cleaner slices. Serve with garnishes like chopped cilantro or green onions.

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